Abbeville County	001	Abbeville	1785	Ninety-Six District	Abbeville, France	24,872	511 sq mi
(1,323 km2)	State map highlighting Abbeville County
Aiken County	003	Aiken	1871	Barnwell, Edgefield, Lexington, and Orangeburg	William Aiken, founder of the South Carolina Canal and Railroad Company	167,458	1,080 sq mi
(2,797 km2)	State map highlighting Aiken County
Allendale County	005	Allendale	1919	Barnwell and Hampton	P.H. Allen, first postmaster of the new county	9,045	413 sq mi
(1,070 km2)	State map highlighting Allendale County
Anderson County	007	Anderson	1826	Pendleton District	Robert Anderson, American Revolutionary War general and Southern surveyor	196,569	757 sq mi
(1,961 km2)	State map highlighting Anderson County
Bamberg County	009	Bamberg	1897	Barnwell	Francis Marion Bamberg, Confederate general in the American Civil War	14,434	395 sq mi
(1,023 km2)	State map highlighting Bamberg County
Barnwell County	011	Barnwell	1798	Orangeburg	John Barnwell, South Carolina State Senator and prisoner of war during the American Revolution	21,483	557 sq mi
(1,443 km2)	State map highlighting Barnwell County
Beaufort County	013	Beaufort	1769	1769 Judicial District	Henry Somerset, 1st Duke of Beaufort, colonial proprietary landowner	183,149	576 sq mi
(1,492 km2)	State map highlighting Beaufort County
Berkeley County	015	Moncks Corner	1882	Charleston	William Berkeley, colonial proprietary governor and landowner	210,898	1,228 sq mi
(3,181 km2)	State map highlighting Berkeley County
Calhoun County	017	St. Matthews	1908	Lexington and Orangeburg	John C. Calhoun, U.S. Senator from South Carolina and states' rights advocate	14,796	392 sq mi
(1,015 km2)	State map highlighting Calhoun County
Charleston County	019	Charleston	1769	1769 Judicial District	King Charles II of England	396,484	1,358 sq mi
(3,517 km2)	State map highlighting Charleston County
Cherokee County	021	Gaffney	1897	Spartanburg, Union, and York	Cherokee Native Americans	56,646	397 sq mi
(1,028 km2)	State map highlighting Cherokee County
Chester County	023	Chester	1785	Camden District	Chester, Pennsylvania	32,181	586 sq mi
(1,518 km2)	State map highlighting Chester County
Chesterfield County	025	Chesterfield	1798	Cheraws District	Philip Dormer Stanhope, 4th Earl of Chesterfield, an Enlightenment-era scholar, government official, and member of the British House of Lords	46,013	806 sq mi
(2,088 km2)	State map highlighting Chesterfield County
Clarendon County	027	Manning	1855	Sumter	Edward Hyde, 1st Earl of Clarendon, colonial proprietary landowner	33,951	696 sq mi
(1,803 km2)	State map highlighting Clarendon County
Colleton County	029	Walterboro	1800	Charleston	John Colleton, colonial proprietary landowner	37,923	1,133 sq mi
(2,934 km2)	State map highlighting Colleton County
Darlington County	031	Darlington	1785	Cheraws District	Darlington, England	67,234	567 sq mi
(1,469 km2)	State map highlighting Darlington County
Dillon County	033	Dillon	1910	Marion	J.W. Dillon, founder of the Wilson Short Cut Railroad	30,858	407 sq mi
(1,054 km2)	State map highlighting Dillon County
Dorchester County	035	St. George	1868	Berkeley and Colleton	Dorchester, Massachusetts	153,773	577 sq mi
(1,494 km2)	State map highlighting Dorchester County
Edgefield County	037	Edgefield	1785	Ninety-Six District	Disputed; either its location on the edge of the state or Edgefield, Norfolk, England	26,358	507 sq mi
(1,313 km2)	State map highlighting Edgefield County
Fairfield County	039	Winnsboro	1785	Camden District	The county's fair fields, as described by colonial governor Charles Cornwallis	22,653	710 sq mi
(1,839 km2)	State map highlighting Fairfield County
Florence County	041	Florence	1888	Clarendon, Darlington, Marion, and Williamsburg	Florence Harllee, daughter of Wilmington and Manchester Railroad founder W.W. Harllee	138,742	804 sq mi
(2,082 km2)	State map highlighting Florence County
Georgetown County	043	Georgetown	1769	1769 Judicial District	King George II of Great Britain	61,399	813.55 sq mi
(2,107 km2)	State map highlighting Georgetown County
Greenville County	045	Greenville	1786	Washington District	Nathanael Greene, Revolutionary War general	498,766	795 sq mi
(2,059 km2)	State map highlighting Greenville County
Greenwood County	047	Greenwood	1897	Abbeville and Edgefield	Greenwood Plantation, the home of John McGee, the county's largest landowner	70,133	463 sq mi
(1,199 km2)	State map highlighting Greenwood County
Hampton County	049	Hampton	1787	Beaufort	Wade Hampton, Congressman from South Carolina and once the nation's wealthiest citizen	19,922	563 sq mi
(1,458 km2)	State map highlighting Hampton County
Horry County	051	Conway	1801	Georgetown	Peter Horry, Revolutionary War general	322,342	1,255 sq mi
(3,250 km2)	State map highlighting Horry County
Jasper County	053	Ridgeland	1912	Beaufort and Hampton	William Jasper, Revolutionary War sergeant	28,465	700 sq mi
(1,813 km2)	State map highlighting Jasper County
Kershaw County	055	Camden	1798	Claremont, Fairfield, Lancaster, and Richland	Joseph Kershaw, one of the county's pioneering settlers	64,097	740 sq mi
(1,917 km2)	State map highlighting Kershaw County
Lancaster County	057	Lancaster	1798	Camden District	Lancaster County, Pennsylvania	89,594	555 sq mi
(1,437 km2)	State map highlighting Lancaster County
Laurens County	059	Laurens	1785	Ninety-Six District	Henry Laurens, president of the Second Continental Congress and prisoner of war during the American Revolution	66,777	724 sq mi
(1,875 km2)	State map highlighting Laurens County
Lee County	061	Bishopville	1902	Darlington, Kershaw, and Sumter	Robert E. Lee, Confederate general during the Civil War	17,635	411 sq mi
(1,064 km2)	State map highlighting Lee County
Lexington County	063	Lexington	1804	Orangeburg	Battle of Lexington, opening skirmish of the Revolutionary War	286,196	758 sq mi
(1,963 km2)	State map highlighting Lexington County
Marion County	067	Marion	1800	Georgetown	Francis Marion, Revolutionary War general	31,726	494 sq mi
(1,279 km2)	State map highlighting Marion County
Marlboro County	069	Bennettsville	1785	Cheraws District	John Churchill, 1st Duke of Marlborough, English general, diplomat, and confidant of monarchs	26,945	485 sq mi
(1,256 km2)	State map highlighting Marlboro County
McCormick County	065	McCormick	1914	Abbeville, Edgefield, and Greenwood	Cyrus McCormick, inventor of the mechanical reaper and founder of International Harvester	9,643	394 sq mi
(1,020 km2)	State map highlighting McCormick County
Newberry County	071	Newberry	1785	Ninety-Six District	Disputed; possibly Newbury, Berkshire, England, or from early settlers' notion that the landscape was as "pretty as a new berry"	38,079	647 sq mi
(1,676 km2)	State map highlighting Newberry County
Oconee County	073	Walhalla	1868	Pickens	Oconee Native Americans	76,355	674 sq mi
(1,746 km2)	State map highlighting Oconee County
Orangeburg County	075	Orangeburg	1769	1769 Judicial District	Prince William V of Orange	87,903	1,128 sq mi
(2,922 km2)	State map highlighting Orangeburg County
Pickens County	077	Pickens	1826	Pendleton District	Andrew Pickens, Governor of South Carolina	122,863	512 sq mi
(1,326 km2)	State map highlighting Pickens County
Richland County	079	Columbia	1799	Camden District	The county's rich soil	409,549	772 sq mi
(1,999 km2)	State map highlighting Richland County
Saluda County	081	Saluda	1896	Edgefield	Saluda River	20,197	462 sq mi
(1,197 km2)	State map highlighting Saluda County
Spartanburg County	083	Spartanburg	1785	Ninety-Six District	"Spartan Regiment" of the state militia, which was the key force for victory in the Revolutionary War Battle of Cowpens	301,463	819 sq mi
(2,121 km2)	State map highlighting Spartanburg County
Sumter County	085	Sumter	1798	Claremont, Clarendon, and Salem	Thomas Sumter, Revolutionary War general and U.S. Senator from South Carolina	107,396	682 sq mi
(1,766 km2)	State map highlighting Sumter County
Union County	087	Union	1798	Ninety-Six District	Union Church, the first Christian place of worship in the area	27,673	516 sq mi
(1,336 km2)	State map highlighting Union County
Williamsburg County	089	Kingstree	1802	Georgetown District	King William III of England	31,955	937 sq mi
(2,427 km2)	State map highlighting Williamsburg County
York County	091	York	1798	Camden District	York County, Pennsylvania	258,526	696 sq mi
(1,803 km2)	State map highlighting York County